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傅里叶变换红外光谱学显微成像(FTIRI)将傅里叶变换红外光谱测量和微区成像技术有机结合起来,同时采集样品的分子光谱和表面形貌信息,可以获得样品空间各微区位置的组成和分子结构信息.本文简述了该成像系统的构成、特点和工作原理,介绍了FTIRI在生物医学/光学领域新开辟的关节软骨光谱成像.重点介绍了该技术用于研究正常关节软骨和骨关节炎软骨所取得的代表性成果和进展,分析了部分局限性及其在该领域的未来发展前景.
Fourier Transform Infrared Spectroscopy (FTIRI) Fourier Transform Infrared Spectroscopy and Micro-Area Imaging combine organically and acquire the molecular spectrum and surface topography information of the sample to obtain the position of each micro-area in the sample space The composition and molecular structure of the imaging system.This paper briefly describes the composition, characteristics and working principle of the imaging system, and introduces the new FTIRI spectroscopic imaging of articular cartilage in the field of biomedicine / optics.The emphasis is put on the application of this technique in the study of normal articular cartilage And osteoarthritis cartilage obtained by the representative of the results and progress, analysis of some limitations and their future prospects in the field.