C.parvum 是寄生在人肠道上皮细胞的一种原虫。对免疫系统未受损者常引起腹泻、抽搐、恶心和厌食,对免疫受损者(如服用免疫抑制剂或感染 HIV 者)可导致病程延长。目前尚无治疗该原虫病的特效药。作者研究了橙酮、auronols 和α-吡喃酮类对该原虫的体外抑制活性。 C. parvum is a protozoan parasitizing in human intestinal epithelial cells. People who are not immune to the immune system often cause diarrhea, convulsions, nausea, and anorexia, and those who are immunocompromised, such as those who take immunosuppressive agents or who are infected with HIV, can cause prolonged disease. There is currently no cure for the protozoal disease. The authors studied the in vitro inhibitory activity of orange ketones, auronols, and alpha-pyrones on the protozoa.