论文部分内容阅读
目的:观察洁泽2号(JZ2)体外抗阴道毛滴虫的作用。方法:比较不同时间、不同浓度的JZ2、JZ1、N-9及甲硝唑体外抗滴虫的效果。结果:随着药物作用时间的延长和药物浓度的增加,滴虫死亡率增高;相同时间内各药物浓度组滴虫死亡率与对照组比较均有显著性差异(P<0.05);JZ2(0.25±0.0625)mg.ml-1浓度作用2h及(0.125±0.03125)mg.ml-1浓度作用48h滴虫死亡率均达到100%,相同时间内滴虫死亡率高于同浓度的JZ1、N-9及1%甲硝唑(P<0.05)。结论:JZ2有较好的体外抗滴虫作用,其作用效果强于同浓度的JZ1、N-9及1%甲硝唑。
Objective: To observe the effect of JZ2 against Trichomonas vaginalis in vitro. Methods: The effects of anti-trichomoniasis of JZ2, JZ1, N-9 and metronidazole were compared in vitro at different concentrations. RESULTS: With the prolongation of the drug action time and the increase of drug concentration, the mortality of trichomoniasis increased; the mortality of trichomoniasis in each drug concentration group was significantly different from the control group at the same time (P<0.05); JZ2 (0.25) At the same time, the mortality of trichomoniasis reached 100% within a concentration of ±0.0625 mg.ml-1 and (0.125±0.03125)mg.ml-1 for 48 h. The mortality of trichomoniasis was higher than that of JZ1 and N- 9 and 1% metronidazole (P<0.05). Conclusion: JZ2 has a better anti-trichomonas effect in vitro, its effect is stronger than the same concentration of JZ1, N-9 and 1% metronidazole.