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急性暴露于二硫化碳(CS_2)的人可出现意识混浊、谵妄,甚至是致命的。亚急性者可出现躁狂抑郁性精神病、幻觉及自杀倾向。长期低量暴露则可产生多发性神经病、帕金森病、小脑性共济失调及锥体束症状。目前对其发病机理仍不清楚。作者报告一组长期暴露于CS_2的多发性神经病病人,就中枢神经系统症状学、头颅CT、MRI、脑血管造影及颈动脉多普勒超声进行研究。 作者观察了10例41~49岁,长期暴露于CS_2而出现轻到中度多发性神经病的男性病人,他们接受胆固醇、甘油三脂、EKG、EEG、脑CT、脑MRI、颈动脉多普勒
People who are acutely exposed to carbon disulfide (CS_2) can develop confusion, delirium, and even fatal. Subacute people may have manic depressive psychosis, hallucinations and suicidal tendencies. Long-term low-level exposure can produce multiple neuropathies, Parkinson’s disease, cerebellar ataxia and pyramidal tract symptoms. Its pathogenesis is still unclear. The authors report a group of patients with chronic neuropathy who have been exposed to CS_2 for a long time and studied CNS symptomatology, head CT, MRI, cerebral angiography and carotid artery Doppler ultrasound. The authors looked at 10 male patients aged 41-49 who had long-term exposure to CS_2 and had mild to moderate polyneuropathy. They received cholesterol, triglycerides, EKG, EEG, brain CT, brain MRI, carotid Doppler