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IntroductionrnHepatocellular carcinoma ( HCC) is one of the most prevalent malignancies worldwide,with an increasing incidence in the United States and Europe, and the third most common cause of cancer-related death worldwide[1-2] .Based on the GLOBOCAN 2008 estimates, about 748 300 new liver cancer cases and 695 900 cancer deaths occurred worldwide in 2008 ,collected and made available by the World Health Organization ( WHO) [3].