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自1984年开始,作者对催乳素(PRL)与乳腺癌的关系进行了研究,发现PRL可作为进展期乳腺癌的标志物及预后因素。对结直肠癌的研究发现,在男性结直肠癌中具有相同的意义。本文通过对舌癌的免疫组化研究,发现舌癌组织可产生异位PRL,并探讨了PRL与舌癌预后、病程的关系。 作者对1987年1月至1991年12月医院诊治的38例男性舌癌资料进行回顾性分析,对照组为23例年龄相当的健康男性志愿者(吸烟和不吸烟)。临床清理分期采用TNM法,组织学分级采用Broder氏法。所有病例至少随访18个月,由于本组均为晚期病例,
Since 1984, the authors studied the relationship between prolactin (PRL) and breast cancer and found that PRL can be used as a marker and prognostic factor for advanced breast cancer. Research on colorectal cancer has found the same significance in men with colorectal cancer. In this paper, immunohistochemical study of tongue cancer found that tongue cancer tissue can produce heterotopic PRL, and explored the relationship between PRL and tongue cancer prognosis, duration. The authors retrospectively analyzed 38 male tongue cancer data from January 1987 to December 1991 in a hospital setting. The control group consisted of 23 healthy male volunteers (smoking and non-smoking) of comparable age. Clinical clean-up staging using TNM method, histological grading using Broder's method. All cases were followed up for at least 18 months, because this group are late cases,