目的总结重症支原体肺炎的诊断和治疗体会。方法分析48例重症支原体肺炎的临床特征及诊治过程。结果重症支原体肺炎临床特点为持续高热、咳嗽,肺部体征重,伴多系统、多器官损害,大环内酯类抗生素联合激素及利福平治疗有效。结论重症支原体肺炎病程长,病情重,经合理治疗可治愈。 Objective To summarize the diagnosis and treatment of severe mycoplasma pneumonia. Methods 48 cases of severe mycoplasma pneumonia clinical features and diagnosis and treatment process. Results The clinical features of severe Mycoplasma pneumonia were sustained fever, cough, lung signs, with multiple system and multiple organ damage. The combination of macrolide antibiotics and rifampicin was effective. Conclusion Severe Mycoplasma pneumonia has a long course of illness and serious illness, which can be cured by reasonable treatment.