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本文报导了一类新的不对称吸咐诱导剂四环素类抗菌素如四环素、土霉素、金霉素等,它们能被汞阴极吸附,若将它们作为苯乙酮不对称电还原时的手性吸附诱导剂,则所得电解产物α-苯乙醇具有光学活性。其光学收率为4.8～18.5%。产物α-苯乙醇的优势构型与光学收率受手性吸附诱导剂浓度与电极电势及pH等因素的影响。本文讨论了苯乙酮不对称电还原的可能机理。
This paper reports a new class of asymmetric sorption-inducing tetracycline antibiotics such as tetracycline, oxytetracycline and chlortetracycline, which can be adsorbed by mercury cathodes. If they are used as chirality for the asymmetric reduction of acetophenone Adsorption inducing agent, the resulting electrolysis product α-phenyl ethanol has optical activity. The optical yield of 4.8 ~ 18.5%. The predominant configuration and optical yield of the product α-phenylethanol are affected by factors such as concentration of chiral adsorption inducer and electrode potential and pH. This article discusses the possible mechanism of asymmetric reduction of acetophenone.