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病程较长的糖尿病患者常伴有胃运动功能障碍,以上腹部饱胀、餐后加重,厌食,嗳气等为主要症状,1958年Kassander定名为“糖尿病性胃麻痹”。我们用普瑞博思(西沙必利)治疗57例糖尿病性胃麻痹,效果良好,现总结如下。 治疗对象:本组57例,均符合世界卫生组织(WHO)1980年制定的糖尿病诊断标准,男33例,女24例,年龄35~68岁,平均54岁,病程3~14年,平均6.3年。胃麻痹持续时间30~180天,均无肝脏疾患,肝功正常,并经胃镜检查排除胃、十二指肠溃疡、幽门梗阻、肿瘤,所有患者钡餐造影显示胃蠕动波小于2次/分,半小时胃排空小于3/5。 治疗方法:本组病例给予普瑞博思10mg,1日3次,餐前15~30分钟服用,连服4周为1个疗程。
Diabetes patients with longer duration often accompanied by gastric motor dysfunction, the above abdominal fullness, postprandial aggravate, anorexia, belching and other symptoms as the main symptoms, 1958 Kassander named “diabetic stomach paralysis.” We use Puri Boo Si (cisapride) treatment of 57 cases of diabetic gastric paralysis, the effect is good, are summarized as follows. Treatment object: The group of 57 cases, are in line with the World Health Organization (WHO) in 1980 developed diabetes diagnostic criteria, 33 males and 24 females, aged 35 to 68 years, mean 54 years, duration of 3 to 14 years, an average of 6.3 year. Gastroplegia duration of 30 to 180 days, no liver disease, normal liver function, and ruled out by gastroscopy stomach, duodenal ulcer, pyloric obstruction, cancer, all patients with barium meal showed gastric motility wave less than 2 beats / min, Half an hour stomach emptying less than 3/5. Treatment: This group of patients given Puri Boss 10mg, on the 1st 3 times, taking 15 to 30 minutes before meals, and even served 4 weeks for a course of treatment.