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Kelsen博士等研究了440例局限性食管癌病人采用单纯性手术和术前化疗后的总生存率，病人被随机分为术前化疗组（213例）或直接手术组（Th例）。化疗组进行三个疗程的顺铂和氟尿呼唤化疗，在第三个疗程化疗后2－4周内手术，手术后再进行两个疗程的化疗。经过平均55．44个月的研
Dr. Kelsen et al. studied the overall survival rate of 440 patients with localized esophageal cancer after simple surgery and preoperative chemotherapy. Patients were randomly divided into preoperative chemotherapy group (213 cases) or direct surgery group (Th case). The chemotherapy group received three courses of cisplatin and fluorouricum called chemotherapy, and surgery took place within two to four weeks after the third course of chemotherapy, followed by two courses of chemotherapy. After an average of 55.44 months of research