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安眠酮(Methaqualone,Hyminal)的化学名为2-甲基-3-邻甲苯基-4-喹唑酮。起初认为,本品是非成瘾性催眠药,不会产生依赖性,但以后报告本品能产生巴比妥-乙醇型药物依赖性。随着安眠酮的滥用、成瘾、急性中毒和用以自杀等的不断增多,1971年英国将该药纳入“防止药品滥用条例”之列。在日本、德国、阿根廷、澳大利亚和挪威等国也相继发生安眠酮滥用和过量的问题。美国于1965年开始采用本品,由于对短时作用巴比妥类的限制使用,而安眠酮则能任意购得,因而最近也迅速发生严重的滥用情况,为此,有关方面已提出将本品列入第Ⅱ类药物,以控制其生产和使用。
Methaqualone (Hyminal) has the chemical name 2-methyl-3-o-tolyl-4-quinazolinone. At first thought, this product is non-addictive hypnotics, does not produce dependence, but after the report this product can produce barbiturate - ethanol-based drug dependence. With the increasing use of methaqualone, addiction, acute poisoning and the increasing use of suicide, the United Kingdom included the drug in the Prevention of Drug Abuse Ordinance in 1971. In the United States, Japan, Germany, Argentina, Australia and Norway, the problem of abuse and overdose of methaqualone also occurred one after another. Since the United States began using the product in 1965, methamphetamine was arbitrarily purchased due to the limited use of barbiturates for short-term effects. As a result, serious abuses have recently occurred. As a result, Drugs included in the class Ⅱ drugs to control their production and use.