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目的了解不同避孕措施长期使用者生殖道人乳头状瘤病毒(HPV)感染的情况。方法采用聚合酶链反应(PCR)检测服用口服避孕药或使用宫内节育器5年以上的妇女226人宫颈分泌物中HPV DNA,研究对象按避孕措施分成1号片组、复方18-甲组和宫内节育器组。结果三组研究对象的HPV总检出率为14.2%,HPV的检出率复方18-甲组最高,宫内节育器组最低,分别为复方18-甲组20.45%、1号片组11.11%、宫内节育器组8.77%,三组间的差异无统计学意义(P>0.05)。三组中HPV感染者的宫颈均有异常表现,但差异无统计学意义(P>0.05)。结论对有性生活,特别是长期使用避孕措施的妇女提供常规的宫颈涂片检查和HPV检测服务,有助于提高避孕措施使用者的身心健康。
Objective To understand the long-term use of reproductive tract human papilloma virus (HPV) infection in different contraception. Methods HPV DNA in 226 cervical secretions of women taking oral contraceptives or using IUD for more than 5 years were detected by polymerase chain reaction (PCR). Subjects were divided into 1 group, compound 18- A group And IUD group. Results The total detection rate of HPV in the three groups was 14.2%. The detection rate of HPV was the highest in group 18-A and the lowest in group I-I, which was 20.45% in compound 18-A group and 11.11% , 8.77% in intrauterine device group, the difference between the three groups was not statistically significant (P> 0.05). The HPV infection in all three groups showed abnormal cervical findings, but the difference was not statistically significant (P> 0.05). Conclusion The routine cervical smear test and HPV testing services for women who have sex life, especially long-term contraception, help to improve the physical and mental health of users of contraception.