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目的：对５２例有胃食管反流症状的患者进行食管测压及２４小时ｐＨ监测，运用统计学方法分析测压和ｐＨ结果，研究其相关性。方法：应用多导胃肠功能测定仪及便携式ｐＨ监测记录仪，对５２例有胃食管反流症状的患者进行食管测压及２４小时ｐＨ监测。结果：应用多元回归分析发现，ｐＨ的百分比和腹段下食管括约肌（ＬＥＳ）的长度、ＬＥＳ静息压及远端食管的蠕动压明显相关。依据测压及ｐＨ结果，使用ｔ检验方法，结果提示食管蠕动压不仅与ｐＨ＜４的百分化相关，也与酸反流大于５分钟的时间、最长反流时间有关（Ｐ＜００１）。结论：腹段ＬＥＳ的长度及食管下段的蠕动收缩是重要的抗反流屏障。食管酸暴露时间延长减弱食管体部酸清除能力
OBJECTIVE: To evaluate esophageal manometry and 24-hour pH monitoring in 52 patients with gastroesophageal reflux syndrome. The relationship between manometry and pH was analyzed by statistical methods. Methods: Esophageal manometry and 24-hour pH monitoring were performed in 52 patients with gastroesophageal reflux symptoms using a multi-function gastrointestinal function monitor and a portable pH monitor recorder. Results: Using multivariate regression analysis, it was found that the percentage of pH was significantly correlated with the length of esophageal sphincter (LES), resting resting pressure of LES and distal esophageal peristalsis. According to the manometry and pH results, using the t-test, the results suggest that esophageal peristalsis pressure is not only related to the percentage of pH <4, but also to the time of acid reflux greater than 5 minutes and the longest reflux time (P <001 ). Conclusion: The length of the LES and the peristalsis contraction of the lower esophagus are important anti-reflux barriers. Esophageal acid exposure to extend the weakening of the esophagus body acid scavenging capacity