结合慢阻肺（ＣＯＰＤ）的普查，对普查人群中血清总唾液酸（ＴＳＡ）水平进行了检测分析。结果，肺功能异常人群的血清ＴＳＡ水平显著升高，以老年组表现最明显；青年组和老年组的血清ＴＳＡ水平高于中年组。由于慢性咳嗽人群处于缓解期，未发现这部分人群血清ＴＳＡ水平的改变。提示性别和吸烟对血清ＴＳＡ水平无明显影响。 Combined with the general survey of COPD, the levels of serum total sialic acid (TSA) in the general population were analyzed. As a result, serum TSA levels were significantly elevated in patients with abnormal lung function, most notably in the elderly group; serum TSA levels were higher in the young and elderly groups than in the middle-aged group. As chronic cough in remission, no changes in serum TSA levels were found in this population. Suggesting that gender and smoking had no significant effect on serum TSA levels.