目的 :探讨窦口 通道区开放术的“小孔外科”技术及术后粘膜修复和再生的方式。方法 :术中选择性摘除钩突 ,开放筛泡 ,去除中鼻甲及漏斗病变。术中和术后随访分别取鼻粘膜电镜观察。结果 :电镜观察接近术区边缘纤毛柱状细胞增生活跃 ,纤毛的分化趋于成熟 ;而远离边缘的再生上皮细胞分化较慢且不完全。随访 3～ 18个月 ,窦口开放率达 97 5 % ,结论 :再生上皮细胞的修复方式 ,是从术野边缘向中心。传输区的微小损伤手术有利于术后粘膜的修复和再生 Objective: To explore the technique of “small hole surgery” and the way of postoperative mucosal repair and regeneration in the open portal sinus region. Methods: During operation, the uncinate process was selectively removed, the scalp was opened, the middle turbinate and the funnel were removed. Intraoperative and postoperative follow-up were taken nasal mucosa electron microscopy. Results: Electron microscopy showed that the ciliated cells in the edge of the operation area were hyperplastic, and the differentiation of cilia tended to be mature. However, the regenerated epithelial cells far away from the edge differentiated slowly and incompletely. The follow-up ranged from 3 to 18 months. The open rate of ostium was 97.5%. Conclusion: The method of repairing epithelial cells is from the edge of the operative field to the center. Small damage to the transmission area surgery is conducive to postoperative mucosal repair and regeneration