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目的 了解广东省基本消灭丝虫病后(1992-1999年)人群丝虫感染及其抗体变化情况。方法 选择10个监测点采用厚血片法进行病原学监测,并将监测点平均分成两组,分别采用间接免疫荧光抗体试验(IFAT)进行双年(A组)、单年(B组)的血清学监测。结果10个监测点共血检114 437人,未发现微丝蚴血症者。1992-1999年A组血清学监测4次,人群丝虫抗体阳性率依次为6．48%、2．71%、252%及 1.66%。B组共监测4次,人群丝虫抗体阳性率依次为 9．85%、5．42%、2.12%和1.56%。结论 广东省基本消灭丝虫病后10个监测点人群未发现微丝蚴血症者,人群丝虫抗体阳性率呈逐年下降趋势,并已接近非流行区人群的抗体水平。
Objective To understand the prevalence of filarial infections and their antibodies in Guangdong population after basic elimination of filariasis (1992-1999). Methods Thirteen monitoring sites were selected for the etiological diagnosis by means of thick blood chip method. The monitoring points were equally divided into two groups. The patients were randomly divided into two groups: group A (A), group B Serological surveillance. Results A total of 114 437 blood tests were carried out in 10 monitoring sites. No microfilaremia was found. From 1992 to 1999, serological tests of group A were conducted 4 times. The prevalence of filarial antibodies in the population was 6.48%, 2.71%, 252% and 1.66%, respectively. B group were monitored 4 times, the population filarial antibody positive rates were 9.85%, 5.42%, 2.12% and 1.56%. Conclusions There was no microfilariae in 10 monitoring sites after the basic elimination of filariasis in Guangdong Province. The prevalence of filarial antibodies in the population declined year by year, and the antibody levels in the non-endemic areas were approaching.