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随着临床上B超引导下前列腺穿刺活检的开展，前列腺癌的病理诊断中遇到了一些困难．本文收集解放军总医院1980年～1993年间前列腺穿刺活检397例中原诊断前列腺癌的142例，重新复片，发现14例非癌．同时在前列腺增生中发现7例为癌，最后确诊为前列腺癌135例．分析误诊的因素后发现过失诊断的情况是将增生、萎缩、炎细胞、人为挤压四种因素误认为是癌，反之，诊断不足的情况是将高分化癌、导管内癌、癌间质增生、未分化小细胞癌四种因素误认为非癌。上述结果对于提高前列腺活检标本中前列腺癌的诊断有一定意义．
With the clinical B-guided prostate biopsy carried out, the pathological diagnosis of prostate cancer encountered some difficulties. This article collected PLA General Hospital from 1980 to 1993 prostate biopsy in 397 cases of prostate cancer diagnosis of 142 cases, re-complex and found that 14 cases of non-cancerous. At the same time found in 7 cases of benign prostatic hyperplasia of cancer, the final diagnosis of prostate cancer in 135 cases. Analysis of misdiagnosed factors and found that the diagnosis of negligence is hyperplasia, atrophy, inflammatory cells, artificial extrusion of four factors mistaken for cancer, on the contrary, the diagnosis of poorly differentiated carcinoma, ductal carcinoma, cancer mesenchymal hyperplasia , Undifferentiated small cell carcinoma of four factors mistaken for non-cancer. The above results have some significance for improving the diagnosis of prostate cancer in prostate biopsy specimens.