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注射肉毒毒素和透明质酸是目前微创美容治疗最常使用的方法。本文概述了A型肉毒毒素和透明质酸填充剂单独或联合应用对面部各区域皱纹、沟回和容量缺失的治疗方法，总结具体的实施方案和原则，介绍常见并发症及处理方式，为面部年轻化治疗提供参考。“,”The combination of Botulinum toxin and hyaluronic acid is widely used in the field of minimally invasive surgery currently.This article summarizes the methods of facial wrinkles, circuitry and volume loss in the face by a single or combined Type A botulinum toxin and hyaluronic injection, and elucidates the concrete implementation plans and rules. Besides, it introduces the common complications and also supplies related treatments which provide a reference for the face rejuvenation.