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目的研究妥泰单药或联用其他抗癫痫药的临床疗效。方法将我院2009年经确诊为癫痫的43例患者按照不同病程(<1年、1～5年、≥5年)分为三组,并根据不同病情、体重调节用药剂量,稳定期观察时间均为20周。结果总有效率为86.0%。结论妥泰作为一种具有多种作用机制的新型抗癫痫药物,临床试验结果显示有较好的疗效。
Objective To study the clinical efficacy of topiramate alone or in combination with other antiepileptic drugs. Methods 43 cases of epilepsy diagnosed in our hospital in 2009 were divided into three groups according to different course of disease (<1 year, 1 to 5 years, ≥ 5 years), and according to different conditions, dosage of body weight adjustment, observation period of stable period All for 20 weeks. The total effective rate was 86.0%. Conclusion Topotecan as a new anti-epileptic drug with a variety of mechanisms of action, clinical trials showed good efficacy.