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人内皮细胞经一些细胞因子如肿瘤坏死因子(TNF)-α或脂多糖(LPS)处理,可诱导几种粘附分子的表达,并能增强白细胞与内皮细胞表面的粘附。抑制白细胞的粘附或抑制粘附分子的上调是治疗细菌脓毒症和各种炎症性疾病的重要靶点。在寻找具有市场前景的含TNF拮抗活性的欧洲抗炎草本植物中,玉米须的乙醇粗提物显示显著的抑制内
Human endothelial cells treated with several cytokines such as tumor necrosis factor (TNF)-alpha or lipopolysaccharide (LPS) can induce the expression of several adhesion molecules and can enhance the adhesion of white blood cells to the surface of endothelial cells. Inhibiting the adhesion of leukocytes or inhibiting the upregulation of adhesion molecules is an important target for the treatment of bacterial sepsis and various inflammatory diseases. In the search for marketable TNF-antagonistically active European anti-inflammatory herbs, crude ethanol extract of corn silk showed significant inhibition