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目的 652例急性非静脉曲张性上消化道出血(ANVUGIB)患者的调查分析。方法回顾性调查分析652例ANVUGIB患者,调查内容包括患者性别、年龄、文化水平、职业、吸烟饮酒史、内镜诊疗、用药情况等。结果男女比例为2.98∶1。脑力劳动者与体力劳动者比例为0.42∶1。出血原因主要为消化性溃疡和消化道肿瘤。因肿瘤、并发症、饮酒史、既往出血史、低文化水平、高龄是影响病情的主要因素(P<0.01或P<0.05)。所有患者均接受正规静脉质子泵抑制剂治疗。586例患者接受胃镜检查或治疗,手术和介入治疗患者17例,均无一例患者复发。死亡7例,复发10例。结论 ANVUGIB患者中男性发病率高,肿瘤、并发症、饮酒史、既往出血史、低文化水平和高龄是导致病情危重的主要因素。内镜及手术介入治疗疗效好。
Objective To investigate and analyze 652 cases of acute non-variceal upper gastrointestinal hemorrhage (ANVUGIB). Methods A total of 652 ANVUGIB patients were retrospectively investigated. The survey included gender, age, education level, occupation, history of smoking and drinking, endoscopic diagnosis and treatment, and medication status. Results The male-female ratio was 2.98: 1. The ratio of mental laborers to manual laborers is 0.42: 1. The main causes of bleeding peptic ulcer and gastrointestinal cancer. Due to tumor, complications, history of alcohol consumption, previous history of bleeding, low educational level and advanced age were the main factors affecting the disease (P <0.01 or P <0.05). All patients underwent formal venous proton pump therapy. 586 patients underwent endoscopy or treatment, surgery and interventional treatment in 17 patients, none of the patients relapse. 7 died and 10 recurred. Conclusion The incidence of men with ANVUGIB is high. The incidence of cancer, complications, history of alcohol consumption, history of previous haemorrhage, low educational level and advanced age are the major causes of the serious illness in ANVUGIB patients. Endoscopic and surgical intervention is effective.