复旦大学分时制特聘教授吴柏林与哈佛大学学者合作的一项研究发现,减数分裂基因(HFM1)基因突变会导致隐性遗传卵巢早衰。3月6日,相关研究论文发表在国际权威杂志《新英格兰医学杂志》上。卵巢早衰是指卵巢功能衰竭所导致的40岁之前即闭经的现象,具有卵泡刺激素高和雌激素水平低的特点,患病率约为1%,病因复杂。10年前,卵巢早衰被认为是卵巢功能永久丧失,可导致永久性不孕。后来的研究却发现,临床有约50%的卵巢早衰 In a study co-authored by Harvard University scholar Wu Fulin, a distinguished professor at Fudan University, researchers found that mutations in the meiotic gene (HFM1) lead to recessive premature ovarian failure. March 6, related research papers published in the international authoritative magazine “New England Journal of Medicine” on. Premature ovarian failure refers to the phenomenon of amenorrhea caused by ovarian failure before the age of 40, with high follicle-stimulating hormone and low estrogen levels, the prevalence of about 1%, the cause is complicated. 10 years ago, premature ovarian failure is considered a permanent loss of ovarian function can lead to permanent infertility. Later studies have found that about 50% of clinical premature ovarian failure