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肾脏疾病是影响我国人口健康的重大慢病之一。我国肾脏疾病具有自身疾病谱特点,免疫性肾小球疾病是我国最常见的肾脏疾病,也是导致我国尿毒症的最主要的病因,严重危害我国人口健康,并带来了严重的社会和经济负担。迄今为止,由于对免疫性肾小球疾病发生及其发展分子机制认识不足,使得其诊断仍停留于临床综合征和病理形态学诊断水平,缺少有效的疾病分子诊断和分子分型方法。不仅如此,由于在发病机制认识上的局限,免疫性肾小球疾病缺少靶向
Kidney disease is one of the major chronic diseases that affect the health of our population. China’s kidney disease has its own characteristics of the disease spectrum, immune glomerular disease is the most common kidney disease in our country, but also the leading cause of uremia in our country, seriously endangering the health of our population, and brought a serious social and economic burden . So far, due to lack of understanding of the molecular mechanism of immune glomerular disease and its development, its diagnosis still remains in the clinical syndrome and pathomorphological diagnosis, lack of effective disease molecular diagnosis and molecular typing methods. Not only that, due to the limitations of pathogenesis, immune glomerular diseases lack targeting