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目的 观察乙肝病毒携带者肿瘤标志物变化与肝癌发病的关系。方法 将乙肝病毒携带者 6 0例随机分为两组 ,试验组 30例用抗病毒与保肝法治疗 ,对照组不用药物。检测每个病人肿瘤标志物 (AFP、AFU、γ -GT、CEA)的变化。结果 试验组中AFP、AFU、γ -GT、CEA四种肿瘤标志物浓度明显下降 ,而对照组无变化。在此基础上对 80 0 0例HBV携带者的癌变情况进行观察 ,经过 3年的随访研究 ,发现治疗组癌变率明显低于对照组。结论 我们可以通过降低肿瘤标志物预防乙肝转化为肝癌
Objective To observe the relationship between the changes of tumor markers in hepatitis B virus carriers and the incidence of liver cancer. Methods Sixty cases of hepatitis B virus carriers were randomly divided into two groups. 30 cases in the experimental group were treated with antiviral and hepatoprotective drugs, and the control group without drugs. Each patient’s tumor markers (AFP, AFU, γ-GT, CEA) were measured for changes. Results The concentrations of AFP, AFU, γ-GT and CEA in the experimental group were significantly decreased, while the control group did not change. On this basis, 80 0 0 cases of HBV carriers of cancer were observed, after 3 years of follow-up study found that the treatment group was significantly lower than the control group. Conclusion We can prevent the conversion of hepatitis B to liver cancer by reducing tumor markers