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作者在开发新型药物的研究中考察了易附着于局部粘膜的固体剂型,其中一部分已供医疗使用。现将其经验分述如下。 1.子宫粘膜附着型——适用于子宫癌在日本子宫癌占女性癌症的25％,其中90％是子宫颈癌,剩下的10％是子宫体癌。一般情况下,对这些癌的治疗,可通过手术把全子宫摘除。虽然手术后为了抑制癌细胞转移也使用药物对其治疗,但只不过是辅助手段而已。手术切除子宫对于女性来说,无论肉体上还是精神上都是很痛苦的。假如我们
In a study to develop new drugs, the authors examined solid dosage forms that are easily attached to the local mucosa, some of which are already being used for medical purposes. The experience is divided as follows. 1. Uterine mucosa-attached - for uterine cancer Uterine cancer in Japan accounts for 25% of women with cancer, of which 90% are cervical cancer, the remaining 10% of uterine body cancer. Under normal circumstances, the treatment of these cancers, the whole uterus can be removed by surgery. Although the use of drugs to treat cancer metastases is postoperative, it is only an adjunct. Surgical removal of the uterus is painful for women, both physically and mentally. If we