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目的 :探讨超分割放疗食管癌在提高生存率、减少局部复发率与远处转移等方面是否较常规放疗优越。方法 :对 72例食管癌患者随机分成超分割组 (HF)与常规组 (CF) ,采用钴6 0 —γ线三野照射。时间与剂量分割为HF组DT∶1 4GY 次 ,每日 2次 ,间隔 6～ 7h ,总量DT∶75～ 82GY。CF组DT∶2GY 次 ,每日 1次 ,DT∶6 0～ 70GY。结果 :HF组在近期疗效、1、3、5年生存率均优于CF组 ,局部复发率HF组低于CF组。结论 :超分割放疗可减少局部复发率 ,提高生存率
Objective: To explore whether hyperfractionated radiotherapy for esophageal cancer is superior to conventional radiotherapy in improving survival rate, reducing local recurrence rate and distant metastasis. Methods: Seventy-two esophageal cancer patients were randomly divided into two groups: hyperfractionated group (HF) and conventional group (CF), using cobalt 60-γ line three field irradiation. The time and dose were divided into HF group DT: 1GY times, 2 times a day, interval 6 ~ 7h, total DT: 75 ~ 82GY. CF group DT: 2GY times, once daily, DT: 60 ~ 70GY. Results: The short-term efficacy, 1, 3, and 5-year survival rates in the HF group were better than those in the CF group. The local recurrence rate was lower in the HF group than in the CF group. Conclusion : Hyperfractionated radiotherapy can reduce the local recurrence rate and improve the survival rate