树突状细胞参与机体的许多生理、病理过程,在免疫防御、免疫监视、免疫自稳等多方面发挥重要作用。因其具有独特的生物学性质,在肿瘤的形成和发展、感染的控制与播散、移植的排斥与耐受以及自身免疫性疾病发病等方面的作用日益受到重视,成为近年来研究的热点。现就其生物学特性及其在肿瘤、感染、移植及自身免疫病等方面的作用予以综述。 Dendritic cells participate in many physiological and pathological processes of the body and play an important role in many aspects such as immune defense, immune surveillance, and immune self-stabilization. Due to its unique biological properties, its role in the formation and development of tumors, the control and dissemination of infection, the rejection and tolerance of transplantation and the onset of autoimmune diseases have drawn increasing attention and become a hot spot in recent years. Now on its biological characteristics and its role in cancer, infection, transplantation and autoimmune diseases are reviewed.