对22例人工瓣感染性心内膜炎(PVE)患者的临床资料进行分析,结果表明,PVE的临床特征同一般细菌性心内膜炎,但死亡率较高,达72.7%;早期感染多因手术过程污染所致,致病菌以革兰阴性杆菌多见;其次为金黄色葡萄球菌;晚期感染常因呼吸系统感染所致,致病菌多为链球菌;主要死亡原因为心力衰竭和肾功能衰竭. The clinical data of 22 patients with prosthetic endocarditis (PVE) were analyzed. The results showed that the clinical features of PVE were the same as those of general bacterial endocarditis, but the mortality rate was 72.7%. The number of early-stage infections Due to the contamination of the surgical process, the pathogens are more common with Gram-negative bacilli; followed by Staphylococcus aureus; late infections are often caused by respiratory infections, mostly Streptococcus; the main causes of death are heart failure and Renal Failure.