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以大剂量大肠杆菌内毒素粗制品注入狗静脉内造成内毒素休克。蟾酥与山莨菪硷均有一定的抗休克作用,二者合用(蟾山合液)可使疗效明显提高。蟾山合液的疗效可能系两者共同作用,从而较好地抑制弥散性血管内凝血、减少纤维连结素消耗和改善血液流变性及红细胞膜功能。
High-dose E. coli endotoxin crude product was injected into the dog’s vein to cause endotoxin shock. Both wolfberry and hawthorn have a certain anti-shock effect, and the combination of the two (Lushan liquid) can significantly improve the curative effect. The efficacy of Dangshan Hexie may be a combination of the two, so as to better inhibit disseminated intravascular coagulation, reduce the consumption of fibronectin, and improve hemorheology and erythrocyte membrane function.