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近来,已证实血管内凝血对许多疾患的症状的产生可能起重要的作用。血管内凝血可为急性或慢性,也可为局限性或弥漫性,其体征和症状可发生在原发病的活动期,也可出现在抑制期。已发现癌病患者常有亚临床的血管内凝血,表现为凝血蛋白异常、纤维蛋白分解产物增加,或血小板或纤维蛋白原消耗加速。作者查阅了1,459例癌病患者的尸检记录,发现12例似为血管内凝血引起的多灶性脑梗死,并进行了病理分析。
Recently, it has been demonstrated that intravascular coagulation may play an important role in the development of symptoms of many conditions. Intravascular coagulation can be acute or chronic, but also limited or diffuse, the signs and symptoms can occur in the primary disease activity can also occur in the inhibitory phase. It has been found that patients with cancer often have subclinical intravascular coagulation manifested as abnormalities in coagulation proteins, increased fibrinolytic products, or accelerated consumption of platelets or fibrinogen. The authors reviewed the autopsy records of 1,459 cancer patients and found that 12 appeared to be multifocal cerebral infarctions caused by intravascular coagulation and were pathologically analyzed.