肝脏是体内糖代谢和维持血糖稳定的重要器官之一，也是调节血糖的激素，如胰岛素及胰高糖素等，代谢作用的重要场所。据统计肝硬化患者中有70％以上有糖耐量异常［’，’］。对其发生机制国内外已有大量研究。为了进行肝硬化患者非糖刺激下胰岛p细胞功能改变及胰岛素抵抗方面的 The liver is one of the important organs for maintaining glucose metabolism and maintaining blood sugar stability in the body. It is also an important site for regulating the blood sugar hormones such as insulin and glucagon. According to statistics, more than 70% of patients with cirrhosis have impaired glucose tolerance [’,’]. A great deal of research has been done on its mechanism both at home and abroad. For liver cirrhosis patients with non-glucose-stimulated islet p cell function changes and insulin resistance