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目的:分析在肝癌介入术中分别应用丙泊酚与右美托咪麻醉的效果对比。方法:选取郑州人民医院2016年6月至2017年5月收治的87例肝癌介入术患者,按随机数字表法分为观察组、对照组。给予观察组44例患者右美托咪,对照组43例患者给予丙泊酚麻醉。对比两组相关观察指标。结果:手术结束后,对照组患者术中平均应用瑞芬太尼给药量(83.55±17.09)ng·kg~(-1)·min~(-1)显著高于观察组患者术中平均应用瑞芬太尼给药量(65.21±16.44)ng·kg~(-1)·min~(-1);术后苏醒10 min时,对照组患者的心率值(75.32±10.09)次·min~(-1)、平均动脉压值(92.01±10.54)mmHg、呼吸频率值(13.97±2.88)次·min~(-1)、以及脉搏氧饱和度值(98.66±1.22)%与观察组患者的各项指标值相比,差异具有统计学意义(P<0.05)。结论:在肝癌介入术中应用右美托咪定进行麻醉可有效减轻患者的应激反应,保障呼吸频率,降低对心率、平均动脉压等指标影响情况。
Objective: To compare the effects of propofol and dexmedetomil anesthesia in liver cancer intervention. Methods: Eighty-seven patients with hepatocellular carcinoma who were admitted to Zhengzhou People’s Hospital from June 2016 to May 2017 were randomly divided into observation group and control group according to random number table. Forty four patients in the observation group were given dexmedetomib, and 43 in the control group were given propofol anesthesia. Compare two groups of related indicators. Results: After operation, the average intraoperative remifentanil administration volume (83.55 ± 17.09 ng · kg -1 · min -1) in the control group was significantly higher than that in the observation group The remifentanil administration rate was (65.21 ± 16.44) ng · kg -1 · min -1 and the heart rate (75.32 ± 10.09) times · min ~ (-1), mean arterial blood pressure (92.01 ± 10.54) mmHg, respiratory rate (13.97 ± 2.88) min -1, and pulse oxygen saturation (98.66 ± 1.22)% in the observation group The value of each index, the difference was statistically significant (P <0.05). Conclusion: The application of dexmedetomidine anesthesia in liver cancer intervention can effectively reduce the patient’s stress response, protect the respiratory rate, reduce the heart rate, mean arterial pressure and other indicators.