目的　探讨胆囊癌误诊发生的原因 ,寻找预防的方法。方法　对 1990年 6月～ 1999年 6月 2 6例胆囊癌发生误诊的临床资料进行回顾性分析。结果　术前误诊 19例 ,高达 73.1%。并发胆囊其它疾病为主要原因。其中胆囊结石最常见占 73.7% ,其次有慢性胆囊炎急性发作、瓷样胆囊、胆囊息肉样改变。结论　临床上对于 1老年女性有胆囊炎病史多年 ,胆囊萎缩。 2近期出现局部症状加剧或伴消化障碍。 3 B超或 CT影像学检查 ,胆囊壁不规则隆起或胆囊内单发结节短期内体积增大明显 ,均应早期进行预防性胆囊切除 ,常规剖开胆囊标本 ,亦可提高胆囊癌的诊断率 Objective To explore the causes of the misdiagnosis of gallbladder cancer and find ways to prevent it. Methods The clinical data of 26 cases of gallbladder cancer misdiagnosed from June 1990 to June 1999 were analyzed retrospectively. Results 19 cases were misdiagnosed before surgery, up to 73.1%. Complications of gallbladder other diseases as the main reason. Gallstones accounted for 73.7%, followed by acute cholecystitis, porcelain gallbladder, gallbladder polypoid changes. Conclusion Clinically, 1 elderly woman has a history of cholecystitis for many years and gallbladder atrophy. 2 The recent increase in local symptoms or with digestive disorders. 3 B-ultrasonography or CT imaging examination, gallbladder wall irregular uplift or a single nodule in the gallbladder in the short-term increase in volume, should be early preventive cholecystectomy, conventional open gallbladder specimens, can also improve the diagnosis of gallbladder cancer rate