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本研究评估CHA2DS2-VASc积分对合并或不合并心房颤动的心力衰竭人群缺血性卒中、血栓栓塞和死亡的预测能力。研究者应用丹麦全国登记资料进行了前瞻性队列研究,包括2000-2012年间诊断心力衰竭而且未接受抗凝治疗的42987例患者(21.9%合并心房颤动),2012年12月31日结束随访。CHA2DS2-VASc积分(10个可能积分点,高分意味着高风险)根据基线合并心房颤动情况进行分层。终点为诊断心力衰竭1年后缺血性卒中、血栓栓塞和死亡的发生率。没有心房颤动的心力衰竭患者缺血性卒中、血栓栓塞和死亡发生
This study assessed the ability of CHA2DS2-VASc to predict ischemic stroke, thromboembolism, and death in heart failure patients with and without atrial fibrillation. Researchers conducted prospective cohort studies using Danish national registry data, including 42,987 patients (21.9% with atrial fibrillation) diagnosed with heart failure and no anticoagulation between 2000 and 2012 and completed on December 31, 2012. CHA2DS2-VASc points (10 possible integration points, high score means high risk) were stratified based on baseline atrial fibrillation. The endpoint was the incidence of ischemic stroke, thromboembolism and death one year after diagnosis of heart failure. Patients with heart failure without atrial fibrillation have ischemic stroke, thromboembolism, and death