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角膜缘干细胞缺乏是角膜缘干细胞数量或功能下降所致角膜上皮稳态失衡性眼表疾病。国际角膜缘干细胞工作小组于2019和2020年制定并发布了有关角膜缘干细胞缺乏定义、诊断、分期和治疗的国际共识，为角膜缘干细胞缺乏的相关研究和临床诊疗工作提供了标准。为了方便我国眼科医师正确理解和掌握其核心内容，本文就国际共识中的重点和难点内容进行补充和深入解读。n （中华眼科杂志，2021，57：95-99）“,”Limbal stem cell deficiency is an ocular surface disease with the imbalance of corneal epithelial homeostasis caused by decrease of number or weakening of function of limbal stem cells. In 2019 and 2020, the international limbal stem cell deficiency working group developed and released the international consensus on the definition, classification, diagnosis, staging and management of limbal stem cell deficiency, which provided a standard protocol for related research and clinical diagnosis and treatment of limbal stem cell deficiency. In order to help Chinese ophthalmologists to properly understand its core components, there is a need to make in-depth interpretation to the key and difficult contents of the international consensusn . (Chin J Ophthalmol, 2021, 57: 95-99)