浸润性微乳头状癌是一种少见的具有特殊形态学特征以及高淋巴结转移、高淋巴管浸润等预后不良生物学行为的恶性肿瘤。近年来研究发现其可以发生在不同的器官,包括乳腺、膀胱、肺、唾液腺、腮腺、结肠、胆管、胃和卵巢等,染色体异常在其发生、发展过程中发挥了重要作用。作者综述了各器官浸润性微乳头状癌的形态病理学及基础研究进展。 Invasive micropapillary carcinoma is a rare malignant tumor with special morphological characteristics and poor prognosis of high lymph node metastasis and high lymphatic vessel invasion. In recent years, studies have found that it can occur in different organs, including breast, bladder, lung, salivary gland, parotid, colon, bile duct, stomach and ovary, chromosomal abnormalities play an important role in its occurrence and development. The authors reviewed the histopathology and basic research progress of various organs with invasive papillary carcinoma.