急性脑梗塞是神经系统疾病中的常见病、高发病 ,发病率、死亡率均逐年上升。 60、70年代曾有人将尿激酶、链激酶应用于临床治疗急性脑梗塞 ,但由于频发出血而一度停用[1 ] ,随着溶栓新药的出现及溶栓药物治疗心肌梗死的成功 ,人们对溶栓治疗又有了新的认识。1　溶栓治疗的时机 Acute cerebral infarction is a common disease in nervous system diseases, with high incidence, morbidity and mortality all year by year. In the 1960s and 1970s, urokinase and streptokinase were used clinically in the treatment of acute cerebral infarction but were once discontinued due to frequent bleeding [1]. With the emergence of new thrombolytic drugs and the success of thrombolytic drugs in the treatment of myocardial infarction, People have a new understanding of thrombolytic therapy. 1 thrombolytic therapy timing