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目的 为了揭示抽动－ 秽语综合征（ Ｔ Ｓ） 患儿的行为问题及其与事件相关诱发电位（ Ｅ Ｒ Ｐ） 之间的关系。方法 应用 Ｅ Ｒ Ｐ、儿童行为量表（ Ａ Ｃ Ｂ Ｃ） 检测３０ 例 Ｔ Ｓ患儿，并与１５ 例正常对照组患儿比较。结果 Ｔ Ｓ患儿 Ｅ Ｒ Ｐ 与对照组相比较 Ｐ３００ 潜伏期明显延长， Ｔ Ｓ患儿 Ａ Ｃ Ｂ Ｃ 总分显著高于对照组，而且经多元回归分析发现两者呈显著正相关。结论 无论是 Ｅ Ｒ Ｐ 的检测，还是行为评价结果都证实 Ｔ Ｓ 患儿行为问题比较常见，并且认为 Ｅ Ｒ Ｐ是一项评价儿童行为问题有价值的客观指标。
Objective To reveal the behavioral problems in children with Tourette Syndrome (T S) and their relationship to event-related evoked potentials (E R P). Methods 30 children with T S were detected by E R P and Child Behavior Checklist (A C B C), and compared with 15 normal children. Results Compared with the control group, E R P in children with T S significantly prolonged the latent period of P300, and the total score of A C B C in children with T S was significantly higher than that in the control group. The multivariate regression analysis showed that there was a significant positive correlation between E R P and control group. Conclusions Both ERL and behavioral evaluation confirm that behavioral problems are common in T S children and that E R P is a valuable objective measure of children’s behavioral problems.