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目的:探讨雷公藤多苷治疗原发性肾病综合征复发患者的临床疗效。方法:将30例原发性肾病综合征复发患者按治疗方式分为观察组和对照组各15例,均行常规及激素治疗,观察组患者加用雷公藤多苷,随访6个月,比较两组患者的临床疗效、激素减量时间及复发率。结果:观察组患者临床总有效率高、激素减量时间短、临床复发率低,与对照组患者比较差异有统计学意义(P<0.05)。结论:雷公藤多苷治疗原发性肾病综合征复发患者临床疗效好,复发率低,效果满意。
Objective: To investigate the clinical efficacy of tripterygium glycosides in the treatment of patients with recurrent nephrotic syndrome. Methods: Thirty patients with recurrent nephrotic syndrome were divided into observation group and control group according to the way of treatment. Fifteen patients in both observation group and control group were treated with conventional and hormonal therapy. Tripterygium glycosides were added in the observation group and followed up for 6 months. Clinical efficacy of two groups of patients, hormone reduction time and recurrence rate. Results: The total effective rate of clinical observation group, hormone reduction time is short, the clinical recurrence rate is low, compared with the control group patients was statistically significant (P <0.05). Conclusion: Tripterygium glycosides treatment of patients with primary nephrotic syndrome relapse patients with good clinical efficacy, low recurrence rate, the effect is satisfactory.