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目的 观察盐酸帕罗西汀对神经症患者认知功能及预后的作用.方法 将2012年3月至2014年3月收治的66例神经症患者抽签随机均分为两组,对照组给予常规基础治疗,观察组在对照组基础上给予盐酸帕罗西汀片治疗.采用简易精神状态检查表(MMSE)评分、社会功能活动问卷(FAQ)评分及蒙特利尔认知测验(Mo-CA)评分比较两组患者的认知功能;用不良反应量表(TESS)评分、汉密尔顿抑郁量表(HAMD)评分评价患者治疗后的预后情况.结果 治疗后观察组MMSE评分为(26.45 ±1.42)分、FAQ评分(5.78 ±0.65)分、MOCA评分(27.84±1.62)分,较对照组治疗前后显著增高(P＜0.05);治疗8周观察组TESS评分(3.21±2.08)分、HAMD评分(22.34 ±5.48)分较对照组治疗前后显著降低(P＜0.05).结论 盐酸帕罗西汀可以控制神经症患者的抑郁情绪,改善患者的认知功能,提高患者的生活质量,从而改善患者预后.“,”Objective To observe the effect of paroxetine hydrochloride on the cognitive function of patients with neurosis and prognosis.Methods From March 2012 to March 2014 treated 66 cases of patients with neurosis lottery were divided into two groups,the control group given conventional foundation treatment,the observation group in the control group on the basis of paroxetine hydrochloride was given.Table using simple mental state examination (MMSE) score,social function activity questionnaire (FAQ) score (MoCA) and Montreal cognitive test scores to compare the cognitive function of the two groups of patients;With adverse reaction scale (TESS) scores,Hamilton depression scale (HAMD) score evaluation of the prognosis of patients after treatment.Results Observation group after treatment for MMSE score (26.45 ± 1.42) points,faqs score (5.78 ± 0.65) points,MOCA score (27.84 ± 1.62),significantly higher than those the control group before and after treatment (P ＜ 0.05);Treatment for 8 weeks observation group TESS score (3.21 ±2.08) points,HAMD score (22.34 ±5.48) than those the control group before and after treatment significantly reduced (P ＜ 0.05).Conclusion Paroxetine hydrochloride can control the neurosis patients with depression,improve patients'cognitive function,improve the quality of life,so as to improve the prognosis of patients.