我国冠醚工作者已发表冠醚论文540余篇,合成冠醚化合物超过560个,我国冠醚工作者对冠醚化学作出了卓越贡献。本文介绍我国冠醚合成化学的主要成就。 1.冠醚典型冠醚的合成,一般都是沿用Pedersen的经典方法。吴养洁等发明的冠醚合成新方法具有操作简便、反应时间短和成本低等优点。该法已在工厂实现冠醚系列产品的生产。 China’s crown ether workers have published more than 540 articles of crown ether, synthesis of more than 560 crown compounds, crown ether workers in China made outstanding contributions to chemistry. This article describes the main achievements of our country crown ether synthetic chemistry. Crown ether typical crown ether synthesis, are generally follow the classic method of Pedersen. The new method of crown ethers invented by Wu et al. Has the advantages of simple operation, short reaction time and low cost. The law has been in the factory crown crown series of products.