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目的探讨沙培林瘤腔内注射治疗脑胶质瘤的疗效。方法自2000年1月至2004年1月对36例脑胶质瘤病人于手术切除肿瘤后,放置Ommaya囊,瘤腔内注射沙培林治疗。4次为一疗程,定期复查CT随诊,可重复治疗2～3疗程。结果病人反应轻微,耐受性好。CT复查见残余及复发的肿瘤液化、坏死。随访8月～4．5年,存活29例,术后3年以上者21例,2年以上者26例。结论该疗法安全可靠、操作简单,应用于脑胶质瘤术后的病人,可延长其生存期,提高生存质量。
Objective To investigate the therapeutic effect of sarperidol intraluminal injection on glioma. Methods From January 2000 to January 2004, 36 patients with glioma were surgically resected. Ommaya pouch was placed and sarcoma was injected intratumorally. 4 times for a course of treatment, regular review of CT follow-up, repeat treatment of 2 to 3 courses. The results of patients with mild reactions, well tolerated. CT review see residual and recurrent tumor liquefaction, necrosis. Follow up from August to 4.5 years, 29 cases survived, more than 3 years after surgery in 21 cases, more than 2 years in 26 cases. Conclusion The therapy is safe, reliable and easy to operate. It can prolong its survival and improve the quality of life in patients with glioma after operation.