近十年来,研究靶选择性抗肿瘤剂的方法明显增加。化学治疗剂的各种化学改造(如改变它的分配系数、连接免疫学的配体或改变电荷密度),收效不大。为了增加抗肿瘤药物的效应,可将它们包封在特殊的载体中以改变它们在体内的分布,理论上可使药物在肿瘤部位浓集,使其对肿瘤的毒性增加而对全身毒性减少。 In the past decade, there has been a significant increase in the number of studies on target-selective antitumor agents. Various chemical modifications of the chemotherapeutic agent, such as changing its partition coefficient, linking immunological ligands or altering the charge density, are less effective. In order to increase the effect of anti-tumor drugs, they can be encapsulated in a special carrier to change their distribution in the body, in theory, drugs can be concentrated in the tumor site, making it more toxic to the tumor with reduced systemic toxicity.