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了解肢体骨肉瘤患者的引流区淋巴结转移情况,分析其出现的原因及应采取的对策.方法 通过复习病历、手术记录和病理,回顾我院自1980年2月~1997年10月肢体骨肉瘤患者的引流区淋巴结转移病程、化疗情况及当时所采取的措施.结果 72例患者中有7例出现引流区淋巴结转移,占 9. 7％,保肢手术后引流区淋巴结转移5例,占 9.4％(5/53).7例患者均未接受正规方案化疗,可能是导致淋巴结转移的重要原因.6例患者在发现淋巴结转移后半年至两年内死亡,1例经淋巴结清扫术已存活12年.结论在骨肉瘤转移中,淋巴转移虽占较小比例,但应引起临床医生的重视,它同血行转移一样都是肿瘤发展至晚期的标志,一旦发生,推测预后不良.因此应尽早行根治性淋巴结清扫术,并辅以有效的化疗,争取挽救患者的最后机会.“,”Objective To review cases of osteosarcoma with regional lymphatic metastasis, and analyze the reasons and the managements. Methods The history records of patients with osteosarcoma and regional lymphatic metastasis during 1980 to 1997 were reviewed. The course of illness, the operation notes and pathologic results, and the methods of chemotherapy were analysed retrospectively. Results Seven cases with regional lymphatic metastasis was found among 72 cases (9. 7% ), 5 cases with regional lymphatic metastasis after limb survival surgery was found (9. 4%, 5/53). All the 7 cases did not have adequate chemotherapy. Six cases died between half to two years after diagnosis of lymphonode metastasis. Conclusion Though the cases with lymphatic metastasis were few, yet appropriate attention should be paid to; lymphatic metastasis indicates late stage of the tumor lesion, giving a poor prognosis and radical lymphadenectomy should be done as soon as possible, following with an effective chemotherapy regime to strive for the best outcome.