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目的:了解恩施州2010-2011年儿童流感流行的情况,为开展流感防治工作提供依据。方法:对2010年1月-2011年12月期间儿童流感病例采集咽拭子,用荧光定量PCR方法进行流感病毒核酸检测。结果:2010年-2011年共采集咽拭子标本970份,共检测到阳性标本113份,流感病毒核酸阳性率为11.6%(113/970)。经分型鉴定甲型H1N1流感病毒21份,季节性H3N2流感病毒38份,季节性H11份,季节性A未分型3份,B型流感51份。2010年1-4月以B型流感为主,5-6月没有流感活动,7-11月主要以季节性H3N2为主;2011年1-3月主要以新甲H1N1为主,同时伴B型流感流行,5-9月没有流感活动,10-12月主要是B型流感为主。结论:恩施州流感流行期以春秋冬三季为主,主要是季节性H3N2、新甲H1N1、B型毒株混合流行,儿童流感没有性别之分,以7-10岁儿童的感染率较高。
Objective: To understand the epidemic situation of children in Enshi Prefecture from 2010 to 2011, and to provide basis for prevention and control of influenza. Methods: Throat swabs were collected from childhood flu cases from January 2010 to December 2011, and the influenza virus nucleic acid was detected by fluorescence quantitative PCR. Results: A total of 970 pharyngeal swabs were collected from 2010 to 2011. A total of 113 positive samples were detected. The positive rate of influenza virus nucleic acid was 11.6% (113/970). 21 strains of influenza A (H1N1) virus, 38 strains of seasonal H3N2 influenza virus, 11 seasonal H11, 3 seasonal A non-subtype and 51 influenza B were identified by typing. From January to April 2010, influenza B was the mainstay, with no influenza activity from May to June, mainly from seasonal H3N2 from July to November. From January to March 2011, the main influenza virus was H1N1, with B Type influenza, no flu activity in May-September, mainly in type B and influenza in 10-12 months. CONCLUSIONS: The epidemic period of Enshi was dominated by three seasons of spring, autumn and winter, mainly seasonal H3N2 and new H1N1 and B strains. The prevalence of influenza in children was not divided by sex, and the prevalence rate among children aged 7-10 years was higher.