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应用PCR方法对哈尔滨地区的3682名孕妇及348名非孕妇女进行弓形体感染的调查。研究证实:哈尔滨市孕妇弓形体感染率为2.42%。其中孕早期1.99%,孕中期1.71%,孕晚期3.46%,新生儿脐血感染率0.62%;非孕妇女弓形体感染率1.44%。哈尔滨地区为弓形体感染低发区,与孕妇感染相关的高危因素是:有动物接触史(以猫为主);不良饮食习惯(食用生菜、未熟透肉类);异常孕产史,与对照组相比较,有显著差异(P<0.05)。同时也证实PCR方法是检测弓形体感染的可靠方法,其与影像学(CT、B超,彩超)技术联合应用是筛查弓形体感染所致先天畸形的有效手段。
Toxoplasma gondii infection in 3682 pregnant women and 348 non-pregnant women in Harbin was investigated by PCR. Study confirmed: Toxoplasma infection rate of pregnant women in Harbin was 2.42%. Among them, 1.99% in early pregnancy, 1.71% in second trimester, 3.46% in third trimester, neonatal cord blood infection rate of 0.62%; non-pregnant women toxoplasmosis rate was 1.44%. In Harbin, the prevalence of toxoplasmosis is low. The risk factors associated with pregnant women infection are animal contact history (mainly cats), poor eating habits (lettuce and immature meat), abnormal pregnancy history, and control There were significant differences between the two groups (P <0.05). At the same time, PCR method is also proved to be a reliable method to detect toxoplasmosis. It is an effective method to screen congenital malformation caused by toxoplasmosis in combination with imaging (CT, B ultrasound and color Doppler ultrasound).