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目的观察丹参注射液联合尼莫地平治疗高血压脑出血的治疗效果。方法将206例高血压脑出血患者随机分为试验组和对照组各103例。2组患者均给予常规治疗,对照组患者采用丹参注射液治疗,试验组采用丹参注射液联合尼莫地平治疗。比较2组患者的治疗效果、治疗前后的欧州卒中量表(ESS)和血肿吸收、不良反应等情况。结果试验组治疗的总有效率为90.3%高于对照组的74.8%,差异有统计学意义(P<0.05);治疗10、15d后2组患者的ESS评分均低于治疗前,血肿量均小于治疗前,且试验组改善幅度大于对照组,差异均有统计学意义(P<0.05);2组患者不良反应发生率差异无统计学意义(P>0.05)。结论采用丹参注射液联合尼莫地平治疗高血压脑出血能够有效改善患者的神经功能,加快血肿吸收,疗效显著。
Objective To observe the therapeutic effect of Danshen injection combined with nimodipine on hypertensive intracerebral hemorrhage. Methods 206 cases of hypertensive intracerebral hemorrhage were randomly divided into experimental group and control group of 103 cases. The patients in both groups were given routine treatment. The patients in the control group were treated with Salvia miltiorrhiza injection. The treatment group was treated with Danshen injection combined with nimodipine. The effects of treatment, the European stroke scale (ESS) and hematoma absorption and adverse reactions before and after treatment were compared between the two groups. Results The total effective rate of the experimental group was 90.3% higher than that of the control group (74.8%), the difference was statistically significant (P <0.05). The ESS scores of the two groups after treatment were lower than those before treatment and hematoma (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion Danshen injection combined with nimodipine in the treatment of hypertensive intracerebral hemorrhage can effectively improve the neurological function of patients and accelerate the absorption of hematoma with a significant effect.