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目的观察胃食管反流病患者内镜检出反流性食管炎情况及疗效。方法对462例有烧心等反流症状的患者行胃镜检查,根据镜下特点分为反流性食管炎(RE)组和非糜烂性反流病(NERD)组,两组患者同时给予2周莫沙比利及雷贝拉唑治疗,观察疗效。结果 462例患者中仅有125例有反流性食管炎,337例内镜检查无异常;两组患者在疗效上无差异(P>0.05)。结论反流症状与内镜表现不符,无论内镜下表现如何,莫沙比利与雷贝拉唑联合试验性短程应用,起到了治疗与诊断的双重效果,是诊断GERD最直接有效的途径。
Objective To observe the endoscopic detection of reflux esophagitis in patients with gastroesophageal reflux disease and its efficacy. Methods Gastroscopy was performed in 462 patients with reflux symptom such as heartburn, and was divided into reflux esophagitis (RE) group and non-erosive reflux disease (NERD) group according to the microscopic features. The patients in both groups were given 2 weeks Mosapride and Rabeprazole treatment, observe the effect. Results Of the 462 patients, only 125 had reflux esophagitis and 337 had no abnormal endoscopy; there was no difference in efficacy between the two groups (P> 0.05). Conclusions Reflux symptoms are inconsistent with endoscopic findings. Both endoscopic and mosapride combined with rabeprazole have the dual effect of treatment and diagnosis, which is the most direct and effective way to diagnose GERD.