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糖尿病视网膜病变是糖尿病的并发症之一,严重影响人类健康和生活质量。探索并积极寻找预防和治疗的方法,是目前面临的主要问题。通过大量的流行病学调查后,发现糖尿病视网膜病变的发生和发展除了与疾病的病程、血糖控制的情况有关外,人群中个体差异的因素也十分重要。有的患者糖尿病的病程很长且血糖控制不良,但随访过程中并未发生糖尿病视网膜病变或其病变程度很轻;而有些患者虽然病程较短且血糖控制良好,但仍然发生了严重的增生性糖尿病视网膜病变,且病变呈明显的家族聚集性趋势。在排除了外界因素的干扰后,考虑发生这一现象的主要原因是由于遗传基因易感性不同所致。
Diabetic retinopathy is one of the complications of diabetes, seriously affecting human health and quality of life. To explore and actively look for ways to prevent and treat is the main problem now. Through a large number of epidemiological investigations, found that the occurrence and development of diabetic retinopathy in addition to disease duration, blood glucose control of the situation, the individual differences in the population factors are also very important. Some patients have a long course of diabetes and poor glycemic control, but diabetic retinopathy does not occur during the follow-up or the severity of the disease is very low. While some patients have a shorter duration and good glycemic control, severe hyperplasia Diabetic retinopathy, and lesions showed a significant family aggregation trend. After excluding the interference of external factors, consider the main reason for this phenomenon is due to genetic susceptibility due to different.