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牙周病的综合治疗,手术疗法占重要地位。为刺激牙周骨袋部分骨组织再生,作者施行牙龈翻瓣手术时在骨袋内植入胶原制剂。胶原是结缔组织基础蛋白,制成的移植物没有毒性和抗原性,同药物和生物活性物质形成络合物,从而加速伤口愈合,并有止血和抗菌作用。作者使用的胶原制剂,含胶原89%～98%,矿物质2%～5%,湿度16%～17%,pH6.8～7.5。先用30只大鼠进行实验,安眠朋钠麻醉下在大鼠背部沿脊柱两侧作切口长10mm～15mm,左侧植入胶原制剂0.2g,右
Comprehensive treatment of periodontal disease, surgical treatment occupies an important position. In order to stimulate the regeneration of part of the bone tissue in the periodontal ligament, collagen preparations were implanted in the bone pocket during the operation of the gum flap. Collagen is a connective tissue basal protein, made of graft toxicity and antigenicity, with the drug and bioactive substances to form complexes to accelerate wound healing, and have a hemostatic and antibacterial effect. The collagen preparation used by the author contains 89-98% of collagen, 2-5% of minerals, 16-17% of humidity and pH 6.8-7.5. Experiments with 30 rats first, sleep sleep under sodium anesthesia in the back of the rat along both sides of the spine for incision length 10mm ~ 15mm, the left implant collagen preparations 0.2g, right